Treatments of bipolar disorder and their brain effects
of Bipolar Disorder and alteration on the brain
reduced glial cell number in the prefrontal cortex of patients (paper 1)
upregulated activities of the protein kinase A and C pathways (paper 1, 2)
changes in neurotransmission (paper 3)
hippocampal neurons of patients with BD (paper 1,3)
2. Lithium treatment and possible mechanisms in the brain.
a. Use of induced pluripotent stem-cell (iPSC) for hyperactive action-potential firing that can be lowered by Lithium treatment.
